23andMe (and You, and Everyone Else) (Ep. 378)

The revolution in home DNA testing is giving consumers important, possibly life-changing information. It’s also building a gigantic database that could lead to medical breakthroughs. But how will you deal with upsetting news? What if your privacy is compromised? And are you prepared to have your DNA monetized? We speak with Anne Wojcicki, founder and C.E.O. of 23andMe.

Evolution, Accelerated (Ep. 291 Rebroadcast)

A breakthrough in genetic technology has given humans more power than ever to change nature. It could help eliminate hunger and disease; it could also lead to the sort of dystopia we used to only read about in sci-fi novels. So what happens next?

The Most Ambitious Thing Humans Have Ever Attempted (Ep. 333)

Sure, medical progress has been astounding. But today the U.S. spends more on healthcare than any other country, with so-so outcomes. Atul Gawande — cancer surgeon, public-health researcher, and best-selling author — has some simple ideas for treating a painfully complex system.

Nurses to the Rescue! (Ep. 309)

They are the most-trusted profession in America (and with good reason). They are critical to patient outcomes (especially in primary care). Could the growing army of nurse practitioners be an answer to the doctor shortage? The data say yes but — big surprise — doctors’ associations say no.

The Demonization of Gluten (Ep. 305)

Celiac disease is thought to affect roughly one percent of the population. The good news: it can be treated by quitting gluten. The bad news: many celiac patients haven’t been diagnosed. The weird news: millions of people without celiac disease have quit gluten – which may be a big mistake.

These Shoes Are Killing Me! (Ep. 296)

The human foot is an evolutionary masterpiece, far more functional than we give it credit for. So why do we encase it in “a coffin” (as one foot scholar calls it) that stymies so much of its ability — and may create more problems than it solves?

Evolution, Accelerated (Ep. 291)

A breakthrough in genetic technology has given humans more power than ever to change nature. It could help eliminate hunger and disease; it could also lead to the sort of dystopia we used to only read about in sci-fi novels. So what happens next?

There’s A War On Sugar. Is It Justified? (Ep. 285)

Some people argue that sugar should be regulated, like alcohol and tobacco, on the grounds that it’s addictive and toxic. How much sense does that make? We hear from a regulatory advocate, an evidence-based skeptic, a former F.D.A. commissioner — and the organizers of Milktoberfest.

Bad Medicine, Part 3: Death by Diagnosis (Ep. 270)

By some estimates, medical error is the third-leading cause of death in the U.S. How can that be? And what's to be done? Our third and final episode in this series offers some encouraging answers.

Bad Medicine, Part 2: (Drug) Trials and Tribulations (Ep. 269)

How do so many ineffective and even dangerous drugs make it to market? One reason is that clinical trials are often run on “dream patients” who aren’t representative of a larger population. On the other hand, sometimes the only thing worse than being excluded from a drug trial is being included.