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Search Results for: randomized controlled trial

Episode 201

How Do We Know What Really Works in Healthcare?

A lot of the conventional wisdom in medicine is nothing more than hunch or wishful thinking. A new breed of data detectives is hoping to change that.

Episode 41

Dr. Bapu Jena on Why Freakonomics Is the Best Medicine

…M.D. He’s also Steve’s former student. The two discuss why medicine should embrace econ-style research, the ethics of human-challenge trials, and Bapu’s role in one of Steve’s, ahem, less-than-successful experiments….

Episode 13

When Bapu Met Levitt

…of a conversation between Steve and Bapu from Steve’s podcast, People I (Mostly) Admire, where they cover everything from the ethics of human-challenge trials to why Bapu decided to start…

Episode 61

Should You Bother Getting a Colonoscopy?

Colonoscopy is strongly recommended for Americans over 45. But a new study suggests its benefits have been overstated. Should we change how we screen for colorectal cancer?…

Episode 269

Bad Medicine, Part 2: (Drug) Trials and Tribulations (Replay)

How do so many ineffective and even dangerous drugs make it to the market? One reason is that clinical trials are often run on “dream patients” who aren’t representative of…

Episode 269

Bad Medicine, Part 2: (Drug) Trials and Tribulations

How do so many ineffective and even dangerous drugs make it to market? One reason is that clinical trials are often run on “dream patients” who aren’t representative of a…

Episode 268

Bad Medicine, Part 1: The Story of 98.6 (Replay)

…the first episode of a three-part series, we look at the grotesque mistakes produced by centuries of trial-and-error, and ask whether the new era of evidence-based medicine is the solution….

Episode 449

How to Fix the Incentives in Cancer Research

…especially hard to detect and treat. Pancreatic cancer, for instance, is nearly always fatal. A new clinical-trial platform could change that by aligning institutions that typically compete against one another….

Episode 268

Bad Medicine, Part 1: The Story of 98.6

…the first episode of a three-part series, we look at the grotesque mistakes produced by centuries of trial-and-error, and ask whether the new era of evidence-based medicine is the solution….

Episode 70

You Make Me Feel Like a Natural Experiment

Nobel Prize winner Joshua Angrist explains how the draft lottery, the Talmud, and West Point let economists ask — and answer — tough questions….

Episode 23

Is the Placebo Effect for Real?

In Latin, the word “placebo” means “I shall please.” In the medical world, placebos mean something … well, a little different. Bapu Jena walks us through the thorny world of…

Episode 66

Does Health Insurance Make You Healthier?

It’s a surprisingly hard question to answer. Bapu talks with a health economist about a natural experiment that led to some unexpected findings….

Episode 568

Why Are People So Mad at Michael Lewis?

Lewis got incredible access to Sam Bankman-Fried, the billionaire behind the spectacular FTX fraud. His book is a bestseller, but some critics say he went too easy on S.B.F. Lewis…

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Episode 20

Why Are People So Mad at Michael Lewis?

Lewis got incredible access to Sam Bankman-Fried, the billionaire behind the spectacular FTX fraud. His book is a bestseller, but some critics say he went too easy on S.B.F. Lewis…

Episode 51

What Can We Do About the Hardest Patients? (Replay)

A small number of patients with multiple, chronic conditions use a lot of resources. Dr. Jeffrey Brenner found a way to identify and treat them. Could it reduce health-care spending…

Episode 51

What Can We Do About the Hardest Patients?

A small number of patients with multiple, chronic conditions use a lot of resources. Dr. Jeffrey Brenner found a way to identify and treat them. Could it reduce health care…

Episode 524

How Important Is Breastfeeding, Really?

In this special episode of Freakonomics, M.D., host Bapu Jena looks at a clever new study that could help answer one of parenting’s most contentious questions….

Episode 58

How Important Is Breastfeeding, Really?

Can a clever new study shed light on one of parenting’s most elusive and contentious questions?…

Episode 69

Home Sweet … Hospital?

We take it for granted that, when people are acutely ill, they should be in the hospital. Is there a better way?…

Episode 49

Why Don’t We Have a Cure for Alzheimer’s?

Promising drugs keep failing in trials. Allegations of fraud have cast a shadow over the field. An expert explains why Alzheimer’s treatments have been so hard to find — and…

Episode 30

How Do We Know if Alcohol Is Bad for Us?

Getting solid answers in medicine can be hard — especially when the normal tools are off-limits. Dr. Bapu Jena discusses a research method that’s helping to solve some of science’s…

Episode 49

Why Don’t We Have a Cure for Alzheimer’s? (Update)

Promising drugs keep failing in trials. Allegations of fraud have cast a shadow over the field. An expert explains why Alzheimer’s treatments have been so hard to find — and…

Episode 94

The Price of Doing Business with John List

From baseball card conventions to Walmart, John List has always used field experiments to say revolutionary things about economics. He explains the value of an apology, why scaling shouldn’t be…

A New Method to the Freakonomics Madness

…surgery. They take a similar approach when tackling the question of testing physician quality: What you’d really like to do is run a randomized, controlled trial so that when patients…




Episode 21

Should We Pay People to Be Healthier?

Each year, millions of people get sick or die from diseases caused by their own unhealthy behavior. Getting people to change their bad habits – to quit smoking, eat better,…


Episode 202

How Many Doctors Does It Take to Start a Healthcare Revolution?

The practice of medicine has been subsumed by the business of medicine. This is great news for healthcare shareholders — and bad news for pretty much everyone else.

Episode 8

A Playbook for Beating the Next Pandemic

We dig into why Covid-19 caught us so unprepared, and how we can make sure we’re ready for a future public-health crisis, with former F.D.A. director Scott Gottlieb….

Episode 360

Is the Protestant Work Ethic Real?

In the early 20th century, Max Weber argued that Protestantism created wealth. Finally, there are data to prove if he was right. All it took were some missionary experiments in…