The Columbia neuroscientist and psychology professor Carl Hart believes that recreational drug use, even heroin, methamphetamines, and cocaine, is an inalienable right. Can he convince Steve?
By mid-century, 10 million people a year are projected to die from untreatable infections. Can Cassandra, an ethnobotanist at Emory University convince Steve that herbs and ancient healing are key to our medical future?
The former chairman of the Obama administration’s Council of Economic Advisors tells Steve how improv comedy was a better training ground for teaching than a Ph.D. from M.I.T., and why he’s glad he was wrong about the automotive-industry bailout.
Steve loved Michael Lewis’s latest, The Premonition, but has one critique: Why aren’t there even more villains? Also, why the author of best-sellers Moneyball and The Big Short can barely read a page of his first book without cringing.
Stanford professor Carolyn Bertozzi’s imaginative ideas for treating disease have led to ten start-ups. She talks with Steve about the new generation of immune therapy she’s created, and why she might rather be a musician.
Columbia astrophysicist David Helfand is an academic who does things his own way — from turning down job security to helping found a radically unconventional university.
Gene-editing pioneer Jennifer Doudna worries that humanity might not be ready for the technology she helped develop.
Naturalist Sy Montgomery explains how she learned to be social from a pig, discovered octopuses have souls, and came to love a killer that will never love her back.
Palliative physician B.J. Miller asks: Is there a better way to think about dying? And can death be beautiful?
The British art superstar Flora Yukhnovich, the Freakonomist Steve Levitt, and the upstart American Basketball Association were all unafraid to follow their joy — despite sneers from the Establishment. Should we all be more willing to embrace the déclassé?
After a huge false start, electric cars are finally about to flourish. We speak with a technology historian about this all-too-common story, and what it means for innovation everywhere.
Nobel Prize winner Joshua Angrist explains how the draft lottery, the Talmud, and West Point let economists ask — and answer — tough questions.
The British art superstar Flora Yukhnovich, the Freakonomist Steve Levitt, and the upstart American Basketball Association were all unafraid to follow their joy — despite sneers from the Establishment. Should we all be more willing to embrace the déclassé?
Beatrice Fihn wants to rid the world of nuclear weapons. As Russian aggression raises the prospect of global conflict, can she put disarmament on the world’s agenda?
Linguist and social commentator John McWhorter explains how good intentions may be hurting Black America — and where the word “motherf*cker” comes from.
For lots of things, price is an indicator of quality. But what about in health care? Bapu Jena gets some clues from Steve Levitt’s wine tasting experiment, and looks at why shopping for healthcare is so hard.
How psychologist Dan Gilbert went from high school dropout to Harvard professor, found the secret of joy, and inspired Steve Levitt’s divorce.
Soil scientist Asmeret Asefaw Berhe could soon hold one of the most important jobs in science. She explains why the ground beneath our feet is one of our greatest resources — and, possibly, one of our deadliest threats.
As the Supreme Court considers overturning Roe v. Wade, we look back at Steve Levitt’s controversial research on an unintended consequence of the 1973 ruling.
Seth Stephens-Davidowitz combs through mountains of information to find advice for everyday life.
Jane McGonigal designed a game to help herself recover from a traumatic brain injury — and she thinks playing games can help us all lead our best lives.
As the Supreme Court considers overturning Roe v. Wade, we look back at Steve Levitt’s controversial research on an unintended consequence of the 1973 ruling.
Many of us hate to think about future crises. Game designer Jane McGonigal wants to make it fun.
Billionaire John Arnold is figuring out how to do as much good as he can with his wealth. It takes hard work, risk tolerance, and a lot of spending.
“What breed is she?” Every owner of a mixed-breed dog is eventually asked this when out on a walk. But how much do dogs’ breeds — and genes — really tell us about who they are? Alexandra Horowitz asks Soledad O’Brien about her dog Coco’s ancestry (and her own), then talks to a pioneer in the field of canine DNA.
Game theorist Barry Nalebuff explains how he used basic economics to build Honest Tea into a multimillion-dollar business, and shares his innovative approach to negotiation.
Astronomer Jill Tarter spent her career searching for extraterrestrial intelligence. She explains what civilizations from other planets could teach us about our own future.
Khan Academy founder Sal Khan returns to share his vision for a new way to learn — and the conversation inspires Steve to make a big announcement.
When she’s not rescuing chickens from coyotes, Susan Athey uses economics to address real-world challenges — from online ad auctions to carbon capture technology.
The author of Sapiens has a knack for finding the profound in the obvious. He tells Steve why money is fiction, traffic can be mind-blowing, and politicians have a right to say stupid things in private.
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