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Episode No.
Date
Length
No. 269

Bad Medicine, Part 2: (Drug) Trials and Tribulations (Replay)

How do so many ineffective and even dangerous drugs make it to market? One reason is that clinical trials are often run on “dream patients” who aren’t representative of a larger population. On the other hand, sometimes the only thing worse than being excluded from a drug trial is being included.

8/23/17
45:35
No. 268

Bad Medicine, Part 1: The Story of 98.6 (Replay)

We tend to think of medicine as a science, but for most of human history it has been scientific-ish at best. In the first episode of a three-part series, we look at the grotesque mistakes produced by centuries of trial-and-error, and ask whether the new era of evidence-based medicine is the solution.

8/16/17
44:02
No. 256

What Are You Waiting For? (Replay)

Standing in line represents a particularly sloppy — and frustrating — way for supply and demand to meet. Why haven’t we found a better way to get what we want? Is it possible that we secretly enjoy waiting in line? And might it even be (gulp) good for us?

8/9/17
36:19
No. 298

Everything You Always Wanted to Know About Money (But Were Afraid to Ask)

The bad news: roughly 70 percent of Americans are financially illiterate. The good news: all the important stuff can fit on one index card. Here’s how to become your own financial superhero.

8/2/17
43:59
No. 297

The Stupidest Thing You Can Do With Your Money

It’s hard enough to save for a house, tuition, or retirement. So why are we willing to pay big fees for subpar investment returns? Enter the low-cost index fund. The revolution will not be monetized.

7/26/17
48:00
No. 296

These Shoes Are Killing Me!

The human foot is an evolutionary masterpiece, far more functional than we give it credit for. So why do we encase it in “a coffin” (as one foot scholar calls it) that stymies so much of its ability — and may create more problems than it solves?

7/19/17
39:14
No. 295

When Helping Hurts

Good intentions are nice, but with so many resources poured into social programs, wouldn’t it be even nicer to know what actually works?

7/12/17
51:25
No. 294

The Fracking Boom, a Baby Boom, and the Retreat From Marriage

Over 40 percent of U.S. births are to unmarried mothers, and the numbers are especially high among the less-educated. Why? One argument is that the decline in good manufacturing jobs led to a decline in “marriageable” men. Surely the fracking boom reversed that trend, right?

7/5/17
43:54
No. 218

The Harvard President Will See You Now (Replay)

How a pain-in-the-neck girl from rural Virginia came to run the most powerful university in the world.

6/28/17
39:18
No. 293

Why Hate the Koch Brothers? (Part 2)

Charles Koch, the mega-billionaire C.E.O. of Koch Industries and half of the infamous political machine, sees himself as a classical liberal. So why do most Democrats hate him so much? In a rare series of interviews, he explains his political awakening, his management philosophy and why he supports legislation that goes against his self-interest.

6/22/17
38:58
No. 292

Why Hate the Koch Brothers? (Part 1)

Charles Koch, the mega-billionaire C.E.O. of Koch Industries and half of the infamous political machine, sees himself as a classical liberal. So why do most Democrats hate him so much? In a rare series of interviews, he explains his political awakening, his management philosophy and why he supports legislation that goes against his self-interest.

6/21/17
43:18
No. 291

Evolution, Accelerated

A breakthrough in genetic technology has given humans more power than ever to change nature. It could help eliminate hunger and disease; it could also lead to the sort of dystopia we used to only read about in sci-fi novels. So what happens next?

6/14/17
35:40
No. 290

He’s One of the Most Famous Political Operatives in America. America Just Doesn’t Know It Yet.

Steve Hilton was the man behind David Cameron’s push to remake British politics. Things didn’t work out so well there. Now he’s trying to launch a new political revolution — from sunny California.

6/7/17
42:16
No. 289

How Stupid Is Our Obsession With Lawns?

Nearly 2 percent of America is grassy green. Sure, lawns are beautiful and useful and they smell great. But are the costs — financial, environmental and otherwise — worth the benefits?

5/31/17
27:59
No. 288

Are the Rich Really Less Generous Than the Poor?

A series of academic studies suggest that the wealthy are, to put it bluntly, selfish jerks. It’s an easy narrative to swallow — but is it true? A trio of economists set out to test the theory. All it took was a Dutch postal worker’s uniform, some envelopes stuffed with cash, and a slight sense of the absurd.

5/24/17
43:55
No. 287

Hoopers! Hoopers! Hoopers!

As C.E.O. of Microsoft, Steve Ballmer was famous for over-the-top enthusiasm. Now he’s brought that same passion to the N.B.A. — and to a pet project called USAFacts, which performs a sort of fiscal colonoscopy on the American government.

5/17/17
39:21
No. 286

How Big is My Penis? (And Other Things We Ask Google)

On the Internet, people say all kinds of things they’d never say aloud — about sex and race, about their true wants and fears. Seth Stephens-Davidowitz has spent years parsing the data. His conclusion: our online searches are the reflection of our true selves. In the real world, everybody lies.

5/10/17
34:01
No. 226

Food + Science = Victory! (Replay)

A kitchen wizard and a nutrition detective talk about the perfect hamburger, getting the most out of garlic, and why you should use vodka in just about everything.

5/3/17
36:43
No. 285

There’s A War On Sugar. Is It Justified?

Some people argue that sugar should be regulated, like alcohol and tobacco, on the grounds that it’s addictive and toxic. How much sense does that make? We hear from a regulatory advocate, an evidence-based skeptic, a former F.D.A. commissioner — and the organizers of Milktoberfest.

4/26/17
45:36
No. 284

Is Income Inequality Inevitable?

In pursuit of a more perfect economy, we discuss the future of work; the toxic remnants of colonization; and whether giving everyone a basic income would be genius — or maybe the worst idea ever. (Part 2 of the “Earth 2.0” series.)

4/19/17
44:15
No. 283

Earth 2.0: What Would Our Economy Look Like?

If we could reboot the planet and create new systems and institutions from scratch, would they be any better than what we’ve blundered our way into through trial and error? This is the first of a series of episodes that we’ll release over several months. Today we start with — what else? — economics. You’ll hear from Nobel laureate Angus Deaton, the poverty-fighting superhero Jeff Sachs; and many others. (Part 1 of the “Earth 2.0” series.)

4/12/17
45:52
No. 282

Could Solving This One Problem Solve All the Others?

The biggest problem with humanity is humans themselves. Too often, we make choices — what we eat, how we spend our money and time — that undermine our well-being. An all-star team of academic researchers thinks it has the solution: perfecting the science of behavior change. Will it work?

4/5/17
38:37
No. 281

Big Returns from Thinking Small

By day, two leaders of Britain’s famous Nudge Unit use behavioral tricks to make better government policy. By night, they repurpose those tricks to improve their personal lives. They want to help you do the same.

3/29/17
33:39
No. 194

How Safe is Your Job? (Replay)

Economists preach the gospel of “creative destruction,” whereby new industries — and jobs — replace the old ones. But has creative destruction become too destructive?

3/22/17
36:52
No. 280

Why Is My Life So Hard?

Most of us feel we face more headwinds and obstacles than everyone else — which breeds resentment. We also undervalue the tailwinds that help us — which leaves us ungrateful and unhappy. How can we avoid this trap?

3/15/17
33:26
No. 279

Chuck E. Cheese’s: Where a Kid Can Learn Price Theory

The pizza-and-gaming emporium prides itself on affordability, which means its arcade games are really cheap to play. Does that lead to kids hogging the best games — and parents starting those infamous YouTube brawls?

3/8/17
34:41
No. 278

The Taboo Trifecta

Serial entrepreneur Miki Agrawal loves to talk about the bodily functions that make most people flinch. That’s why she’s building a business around the three P’s: periods, pee, and poop.

3/1/17
35:34
No. 277

No Hollywood Ending for the Visual Effects Industry

In their chase for a global audience, American movie studios spend billions to make their films look amazing. But almost none of those dollars stay in America. What would it take to bring those jobs back — and would it be worth it?

2/22/17
59:11
No. 276

Professor Hendryx vs. Big Coal

What happens when a public-health researcher deep in coal country argues that mountaintop mining endangers the entire community? Hint: it doesn’t go very well.

2/15/17
40:01
No. 246

How to Get More Grit in Your Life (Replay)

The psychologist Angela Duckworth argues that a person’s level of stick-to-itiveness is directly related to their level of success. No big surprise there. But grit, she says, isn’t something you’re born with — it can be learned. Here’s how.

2/8/17
42:11
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